Earnings Call Excerpt
Cytokinetics Inc. (CYTK)
Business Update Call
March 31, 2008 8:00 am ET
Executives
Dr. John R. Teerlink - Associate Professor of Medicine
Dr. Andrew A. Wolff - Senior Vice President of Clinical Research and Development and Chief Medical Officer
Dr. John Cleland - Professor of Cardiology
Presentation
Andrew A. Wolff
Good morning everybody, thank you for joining us. For those of you joining us here at the West and then for those listening via webcast, we hope this morning’s discussion will be helpful. With two principal objectives in mind; firstly, we hope to summarize our recently announced positive phase IIa clinical trial results for CK452 within the context of our ongoing clinical trials program for this novel cardiac myosin activator. Secondly, with the assistance of two key opinion leaders, both of whom are active participants in our clinical trials, we hope this morning’s program may provide some clinical perspective on measurements of cardiac performance and relatives to morbidity and mortality outcomes in the treatment of heart failure patients.
As you can see from our agenda, we have a lot to cover in the next hour. Before we start, I’d like to emphasize that we’re both pleased and encouraged by the positive interim results from this our first phase IIa clinical trial of CK-1827452 in heart failure patients. As Andy will outline for you in a moment, we believe that the growing body of clinical data supports the ongoing development of CK-452, its novel mechanism, and [inaudible] well for what we may observe going forward as we continue the promising program. I’d like to take the opportunity to introduce our speakers.
To my right is our first speaker, Dr. John Teerlink. He is Associate Professor of Medicine at the School of Medicine and Director of the Heart Failure Clinic and Clinical Echocardiography at the San Francisco Veteran Affairs Medical Center, University of California, San Francisco. John was awarded a fellowship in the American College of Cardiology in 1999, and the American Heart Association in 2002, and the European Society of Cardiology in 2003. He serves on the AHA National Committee on Heart Failure and Transplantation, is a member of the US Food and Drug Administration’s Cardiovascular and Renal Drug Advisory Committee, and is on multiple committees with the Heart Failure Society of America.
John received his postgraduate clinical cardiology and internal medicine training at UCSF after obtaining his medical degree from Harvard. Next to John is Andy Wolff, Cytokinetics Senior Vice President, Clinical Research and Development, and the company’s chief medical officer. Andy has been a member of our executive team since September 2004 and has made a tremendous impact especially in leading and overseeing the implementation of both our cardiovascular and oncology clinical trials programs. Prior to joining the company, Andy was Chief Medical Officer at CV Therapeutics, and prior to that held various clinical positions at Syntex, now Roche. In addition, he holds an employment in the Cardiology Division of the University of California, San Francisco, where he is currently an associate clinical professor. Andy received his MD from Washoe St. Louis.
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