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BioMarin Pharmaceutical, Inc. Q1 2008 Earnings Call Transcript

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2008-04-29 21:01:06.0

Tags: BioMarin Pharmaceutical Inc.

Question-and-Answer Session

[Operator Instructions]. Your first question comes from the line of Chris Raymond from Robert Baird. Please proceed.

Christopher Raymond - Robert W. Baird

Thanks for taking my question. I just was wondering and I know it's very early in the launch with Kuvan but you know that 509 patients you've initiated therapy. Do you have any kind of read on any confirmed patients you dropped off therapy and this you could provide that number?

Unidentified Company Representative

Sure we've got a relatively small number that we know have dropped off I think the last number I saw was 26 or 29 that was in the high 20s but what we don't know is patients who have dropped off or will be dropping off because they haven't come due to for a refill yet. So please take that numbers, it's not meaningful in terms of trying to extrapolate a response rate.

Unidentified Analyst

Right, right okay. So when you guys talk about number of patient adds per day I know you are saying instead of fluctuate between 9 and 11 and again I understand that it is early in the launch here but have you though t about how the summer months might impact that number you know from perspective you could say summer months it slows down but may be another perspective would be that it sees more kids getting into their physicians and during the summer is that even a logical way of thinking or is it some other way we should be thinking about patient adds during the summer months.

Unidentified Company Representative

You know we have thought about it a fair amount because we have seen with Aldurazyme replacement product that certainly the July and the August months are tougher months for us to maintain the type of compliance we see through the rest of the year how that's going to play out in the Kuvan market I think we are just have to wait and see though. I think both scenarios that you laid out a positive scenario with particularly children not having a school and maybe have even more time for parents to gave them in you know that's s upside more patients being on vacation having their kids away that's potential downside. Emil is flashing me a note here and he is correct and one of the other things that happens during the summer is that there are PKU camps and that is the patients go into PKU camps some of the non treated patients may get exposed to treated patients and word of mouth may increase number of patients asking about therapy. But I think until we go through it summer and have an actual experience whatever we think is going to happen just what we think is going to happen and we are note it until it actually it does.

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